Temperature and Denaturing Substances Influence on Lab-on-a-Chip Electrophoresis

Lab - on - a - Chip Technology —

Hybridoma: On-chip Cell Fusion Lab in a Tube Lab on a Chip

Antibodies have been used for many different applications ranging from basic biological studies to therapeutics. For example, antibodies are used in treatments as wide ranging as cancer care, autoimmune disease therapy, and to prevent rejection of transplanted organs. This requires large quantities of antibodies, which can be supplied via hybridoma generation. Hybridomas are hybrid cell lines f...

Electrostatics and the Lab on a Chip

At the heart of the laboratory on a chip are chemical or biochemical probes designed to detect specific molecules or reaction products. For these probes to perform their function, a microfluidic "plumbing system" is needed to accept samples, then manipulate, dispense, and distribute tiny liquid volumes on the chip. The most promising mechanisms for handling such small quantities of liquid -from...

Fluorescence monitoring of capillary electrophoresis separation in a lab-on-a-chip with monolithically integrated waveguides

Femtosecond-laser-written optical waveguides were monolithically integrated into a commercial lab-on-a-chip to intersect a microfluidic channel. Laser excitation through these waveguides confines the excitation window to a width of 12 μm, enabling high-spatial-resolution monitoring of different fluorescent analytes, during their migration/separation in the microfluidic channel by capillary elec...

Microfluidics Toward a Lab-on-a-Chip

H.A. Stone,1 A.D. Stroock,2 and A. Ajdari3 1Division of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138; email: [email protected] 2School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, New York 14853; email: [email protected] 3Physico-Chimie Théorique, UMR CNRS-ESPCI 7083, ESPCI, 10 rue Vauquelin, 75005 Paris, France; email: armand@...